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KMID : 1143220190620040285
Obstetrics & Gynecology Science
2019 Volume.62 No. 4 p.285 ~ p.289
Long-term survival after intraperitoneal chemotherapy with paclitaxel-cisplatin for recurrent primary peritoneal cancer resistant to multiple lines of intravenous chemotherapy
Hue Hye-Jeong

Kim Ki-Dong
Kim Hyo-Jin
Suh Dong-Hoon
No Jae-Hong
Kim Yong-Beom
Abstract
The long-term survival of heavily pretreated patients with primary peritoneal cancer (PPC) is uncommon. Here, we report on a patient with PPC refractory to multiple lines of intravenous chemotherapy, namely, a combined regimen of paclitaxel and carboplatin, and single regimens of topotecan, docetaxel, cisplatin, and gemcitabine. However, after intraperitoneal (IP) chemotherapy with paclitaxel-cisplatin, the patient's condition improved, and she has been progression-free for more than 4 years. Interestingly, before the IP chemotherapy, the recurrences were limited to the peritoneal cavity. These results suggest that IP recurrence might be a predictor of a good response to IP chemotherapy.
KEYWORD
Peritoneal neoplasms, Neoplasm recurrence, local, Infusions, parenteral, Drug therapy, Ovarian neoplasms
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